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OCTOBER 20, 2005 - WASHINGTON DC

TITAN STENT VS TAXUS STENT

TCT 2005, results study

Dr Pasi Karjalainen from Satakunta Hospital Pori Hospital in Finland presented the data about the Titan stent Pori Registry during the Cardiovascular Research Foundation's 17th Annual Transcatheter Cardiovascular Therapeutics (TCT 2005) scientific symposia moderated by Dr E.Grube.

Dr Karjalainen included 195 consecutive patients treated for angioplasty with the Titan stent manufactured by Hexacath, and made a comparison with a second cohort of consecutive patients treated with the Taxus stent a product of Boston Scientific. The data demonstrated that the use of the Titan stent resulted in a lower overall Major Adverse Cardiac Event (MACE) at 30 days post procedure than with the Taxus stent (0% Vs.5.1%) with a lower rate of sub acute thrombosis for the Titan cohort (0% Vs 3.6%).

Patients were well matched in both cohorts: complex lesion (B/C) 88% for Titan stent Vs 78% for Taxus stent, Reference Vessel Diameter of 2.93mm for the Titan stent Vs. 3.04mm for the Taxus stent, lesion length of 12.9mm for the Titan stent Vs. 13.8 mm for the Taxus stent and percentage of diabetics of 17% for the Titan stent Vs 19% for the Taxus stent.

According to Dr Karjalainen, this study enrolled high risk patients with rates of Acute Myocardial Events of respectively 66% for the Titan stent Vs 44% for the Taxus stent.

The nine month clinical follow up also showed positive results in favor of the Titan stent Vs. the Taxus stent : MACE (death, heart attack, re-vascularization) were of 10.3% Vs 13.7%.

Dr Karjalainen concluded that the Titan stent is a safe and durable treatment option in the real world of unselected patients.

The Titan stent is manufactured by Hexacath: Hexacath stent



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CARDIAC STENT AND STENTING PROCEDURES

Nowadays, living with a cardiac stent is not an handicap. On the contrary, this may become a chance, allowing your body to work correctly at the top of his capacities.

A cardiac stent is a small metal tube inserted into an artery. The stent remains into the artery to hold open it. The stent helps the blood to flow through the artery.

A cardiac stent is positioned into an artery when there is atherosclerosis. Atherosclerosis narrows the pathway for blood and can slow or block it. Stenting makes the artery back to its original diameter and allows normal blood flow.

The stent is inserted through a main artery and pushed to the narrowed part of the artery with a balloon catheter. Once in place, the balloon is inflated to expand the artery (angioplasty). The stent can be expanded during angioplasty or after the procedure.

After the intervention, the cardiac stent will stay in place into the artery to keep the blood flow to its normal level.

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